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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '788e7e6ccf15ce6393ac53456a6f35e85a65e001f8ca0b69fcde52a6079faed3' 
  AND token = 'tkm8U6+AaZCwWHg7jq5MqgPwwA3P6AdrNfwhzzb2wts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}