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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5721d42f28609e6543711791097d850a101575e391c75d9ed71e1c9ce510a76f' 
  AND token = 'xiIfIfAwHB0uFGe8yPjD8BSWrcIDBycduu04MqNcoyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}