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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f41b6d923b137fd3fc40fdda31e170a1d4021f39d588c7b62cdfbf7a27ac9a78' 
  AND token = 'tnagDx0jLTc4QxocPaUGreXlpyskjZC/HI9CbHe2uH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}