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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12eb443007878cd93fb9d283eb8bbbedbfdbe793645dc49561a18299a6cdf48a' 
  AND token = 'dVtE7/KT4yhmd3jketEN92PKeqTdySBVgOebrqLYCrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}