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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a46ed27a8d578f9d56a628a865193a30dcfa3d9c79e97c3461dd1366af0498cc' 
  AND token = 'nNi+nNv2iyiqLbJZ703EX49qSpAkRtSus97dU1oEZcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}