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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd77f2c49abfe51b6df2ec564098f18de5bd130e88fa8a9d12ab642c51b2dbd75' 
  AND token = 'dqkHRDxbYFC6hfMYo97kp7UGZPWq8ioZL5VU+IlG00Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}