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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1566753dd6e85f86396ce409655f5486076dd3684959425144f76fef33a0792' 
  AND token = '1PpihreTERXnDMm/PtVlTgRoMRBaQxprtkRu0NIfqoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}