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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cc0be750d7405c95193b86050ed35683b7d02cb41d4be77b888761162dcf198' 
  AND token = 'vFokNZ2CtJ65Mw2IsPhJdsPDHNPh5bb4VrWOXKMFE5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}