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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a6d2a94dcdc0fb015b1c6859e92f2dee4e954cdfd5f7db8212702c68d3954af' 
  AND token = 'WshfekeUlsojntAuHQ3xDhlhFNVM4zJ/kRxgu23DqqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}