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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87c0a26e2bad3d80ec85772b9250e248f324d6c3f9f9c3219c150a17a6418650' 
  AND token = 'tCwl/Ynq1n946OUYRPQmvkoY2yppBZjI620Fqm4cEik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}