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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed03f766466ed0fc7629e1a9db217a5bc40c0c8dc92c0ec7edeb71f798663630' 
  AND token = 't0GnuzaiGHCePJqo8rwnDHmokV9edGjZUsem3FWqzjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}