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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69b7e3b576bcf7f1fbfc3082cb7a2b69f13760e6e927ae006f3edf687acac58d' 
  AND token = 'Zd4d+sC/BHKxEsC9BVf0cJL5/PUDknZtO+elh76fKkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}