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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a0c07e49f51b1248ab96ba88c095bf4634343f2c21d7a26b879ed58e7abe9b0' 
  AND token = 'Z+fW2Eb0nJV6xy2Td6NU6avXLKeOjxKQFtP0Em/oVNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}