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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03c5b7c83e9b465948ed2cf3715abc4a1bf36c18d34a2dfa9c88dd761d91f446' 
  AND token = 'cROUSseD4sEs5rrJvzV+0bDdeWwRMEyqWn6meBLScII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}