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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4278c58c2a12462ef77dd5d240dd3d877c60b0f5ebd44b62473cd26f98044986' 
  AND token = 'd97gVI6EXnq5rBcL4jBtBaUoG7edVfxc0U8xvjkLQy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}