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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df4cc3db00cf54bd7b36f963f31a1e5b1749f1b12c0ef626b44798c34f5807bf' 
  AND token = 'auPnkKoGFVyy0YDMfC4yi6j6P87yQ4RHpy2ryUSc4PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}