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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e6597812949e8447dc585f51aa7ffce267d787f63f706aca5a3da3153cfa990' 
  AND token = 'VnH7CJBpOdoO9SSYDuKixb7wvKOHfZ0Xtr7in7WRVXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}