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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23c6aea837c8880f31ae22bdbcece2bdd74377a078a981e9b0eff6b6777eab89' 
  AND token = '8Ub09uOQZ1BvuOm7SYBbXpODSOR46Qh7v5OJyrDbMgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}