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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe86ff8f3df1f4e00e80a03ce115d96bea0cc288a686e00ffebfc4ce3610ce0c' 
  AND token = 'CJYVK1UtbicL/mHNJ4y75bzIsW9sEeU/bEhRPsi5v98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}