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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f319e387830427a043937044330c7be4e1ec334df38455d65ef0aacc2a21d0' 
  AND token = 'nnGkQ2glo3LCO1cElHUd2PKyGIXkp8tZSnjoIt0I/dE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}