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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6805b216f36e7f67e642c844fbf299db35098805fb247e5c593cde90bfa89e17' 
  AND token = 'CoM2m/ieFTt/MPJuLBlvTLk57KSHSbgbt3XVvcmc8TQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}