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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5f8ff0ce7df69d83bed8295d02b8c69812bc312dc6029c24ef51ab90a141189' 
  AND token = 'Rm6Rxr4xpzanK0VAxJpJA6m3koWRBZTd7IrD7lkFVy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}