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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a25e2b22549f1d1440bff33905bdf1ea3625f211fbc874f124fd23402b1ffa79' 
  AND token = 'ESjyp/VCnjhKC0ad3FsOzdVzk5fzSq1kKZaCAyCz+h0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}