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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0b458ba5bcaa8a2042a747a2050afbe83e9cd5f8ee291732933016f252ca44f' 
  AND token = 'u+vyVf3btP2ICi64fazC/f1//Y+8qWave+s3WkFt1kI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}