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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4312625f4022e9cda2c8b4863167a41189923ef349f862a18956b005c7843a39' 
  AND token = '6ruBsyM/UN7gKaWRZi7K7yaJfL8jGQOc3hoiyddM3Mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}