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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c212afd73df987c1281ddc38085a02ad472a1177e86bed55ad49bb9840a89a0b' 
  AND token = 't4DMtMpVEB+K51EXd+WuCeRr+A+W2bIRRiFt9KBhSSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}