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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee9e1d20a6b30a655e14fac1582153e5bba9b7f18d0010e9786085e759066b90' 
  AND token = 'lFS/1hChlOHY+LfhNSVHFDD1IqesGqLpOwSxj98xXVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}