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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bb589dcde4e63dec1743ceba69ec21d6e0ed841475a672349ea4d6376660343' 
  AND token = 'DhXKUtT1PT/ymF/6cg8JxVo3qMpnNhepcU5Jda5R9jE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}