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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d6c229d479fe5227237e7e986b5c54cb225c0526ce0be7d93d827ed761d3ab8' 
  AND token = 'zbLi2Mze0mpPpxn+lxp7lmr8zSMCb2+ubpySTMMveE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}