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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '443ea031613bdd768ac6df2353e7675473ccbdd09a7c946494e8a0d8fdd2379d' 
  AND token = '47VR6QamKC1J8SeC42nJAF4+gcgtH9+0de/SGwgbBpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}