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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849ccfd562864e27a4f88f8c7d14299de48b89f175c1744292aaae6bc817c4c2' 
  AND token = 'PorJS/mh/dLy2wZhrGFDWTMZ75vCa0admcYx1azTt3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}