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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f40388512a61640d22901d08d1d59e6210a2c66b1097e7bb188697e9f80775a4' 
  AND token = 'O6WrEKWo7tfS5/7RT3LRKpZKqBsFVBC1Itl1i2ekM4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}