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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e02f52de1b10bc207b27ddcee8a95d79a04dec3a56125ebdd483abc478e4531' 
  AND token = 'f4jlTyS3xpIAan9uHd2Sjj/SS4QtyIiIMUrsoZ14fls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}