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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ec4ee39541f6a0cb1baf23c075ed1492023a21be54a452577e22a7fcb5b07de' 
  AND token = 'rJoqWGZ2UCr2yA2XwY0XpOdNPosbAzslZ2afMWh7zuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}