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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffda3f5c643016f1e73f7e016ea59343a35ac827b47bb23491a8793606824357' 
  AND token = 'ucESOl0WeCFnL2bg14Vi3GLrV6m+ZSnjHS1Boj7uVRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}