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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '095728e652e4c00a957d4e00d602951363155748ca9995bd8163ab66722a4ef3' 
  AND token = 'yDBWX+2PByJnmDQmOOYSrCiooFmrMlIKk6mZhfUQ+R0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}