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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81bc1e91d060390123107af6decf77666e5d07d6ea07282bc7287d46a034b762' 
  AND token = 'aphpGO4w4T+ywBMz/dWY0HRXaSEysgPsP8PA3Ht/SDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}