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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1497b1ba64d9c552fca2f6565d5ede33510049f7c4e3ee96d2372cf17fbd1f02' 
  AND token = 'x/nlexVv10KG4wRa5sUvK2CpYTHD4nEv5TkOB3CZI68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}