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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2141f03f9b65cdb9a1bf08fc1b1ea788bcce3fb30fdd11b552acdbb4885537f9' 
  AND token = 'EZzo2HdceF1OHQtERZ8QzwuXUrSe/zjzNliUUjGfWzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}