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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12cf011d9d6af3097dbd8a935ef2b51604e1d2f9c1bec2b4f690ea0ff743f1c6' 
  AND token = 'Us20KmhDOVRuJxtrPvD2ms1wpVnWR0+4lYu6TgGfEXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}