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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c8b428888cc38dec29c16ad8df8725f82a4602c220dcc05a827e27175b605c3' 
  AND token = 'U4f9oYqvU5IOBzcA2pwy0PbZ9uPFbqo4AInvU6mGC0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}