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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53e5414612f0c789c25e532acc14d846038b455f390aeb9954d71c9ab64edc7e' 
  AND token = 'u1VvjMey1FkT+cspyNeQyLbIgqHRfIuJoeN+v6UnaGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}