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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5306f38bc956864a43b13ac88ef5d5109bbb410aa06b02e80c3210ff9617d33' 
  AND token = '3FoV/J9B3eeK7yxU727gdMGH+ctCQwcOuciMVVvx0GY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}