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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8d6f2aac29c7bd2384f153d0c61abe981dcc43ee3a3f4826d13f1546e4101e3' 
  AND token = '8CpAW+wzCV6S0CUzN5rDi7smnL0rxdCAVeUjqrC/D1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}