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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ea952a62c8e6e10c298bfcd6c500e3c7b9fe89188aa22ccc239017cb67bd71b' 
  AND token = '1a5z8BCMlUwX2qsImyNN5yYUkVLnZ1JxPTYS8dQA4j4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}