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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d4aef8282b330ad2915f775b3b3a29ad08d43c3d0ad41c720c2552b72102709' 
  AND token = 'VWJgcFh//W21z0IAUEYmPzX767J+qlZrrdCAC1AdZTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}