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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a18ccc27b3770e4e80589dce6d124880e7550b7c5378df7c417e6dec737355d' 
  AND token = 'sSDc6zFZofPkb4FaaOvIIbciAUDU6BZ7x8c2u8lBpVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}