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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c16621b1e6db283b3fec0a1b8f78fa929ad07139afef8552009332ee71ed824b' 
  AND token = 'XvQeetR2Ek+EemD6GygU5KEkmb878DltZrR1rNF/lGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}