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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '482cbffbf50f098f1d2b26642121887bb391f1ab19ba189e02343294e07bf240' 
  AND token = 'w9xHTeD3R7h2cU9XweWQAF+R8JFu0K4uUpn9AMR3o2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}