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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5b2df994c7884374fa64f256d67585ce2340025b3432a9a25532e9739a198a8' 
  AND token = '5/tGpPlS1Dy6FOBzEFk0X4xM92XLjaO1ZLWsMs/444I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}